Author

Andrew R. Green

Nottingham University Hospitals NHS TrustORCID 0000-0002-0488-5913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alyssa Synan· 1 shared Anthony S. Malamas· 1 shared Claude Logel· 1 shared David J. ByrneiD· 1 shared Dominik Hainzl· 1 shared Dorothea LescheiD· 1 shared Eloise House· 1 shared Emad A. RakhaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alyssa Synan

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2 papers

Recent·Most cited

Phylogenetic analysis of paired breast carcinomas identifies genetic events associated with clonal recurrence and invasive progression

Tanjina Kader, Maia Zethoven, Sakshi Mahale, Hugo Saunders, Lauren Tjoeka, Rebecca Lehmann, Madawa W Jayawardana, Jia‐Min Pang, Dorothea Lesche, Neeha Rajan, Timothy J. Semple, Jue Er Amanda Lee, Richard Lupat, David J. Byrne, Siobhan Hughes, , Kylie L. Gorringe

The paper analyzes paired breast carcinomas to determine if recurrences are clonal or new tumors, finding 7% are non-clonal by whole exome sequencing.

The Journal of Pathology · Oct 30, 2025Peer-reviewedCancer Biology

A bispecific antibody-drug conjugate targeting pCAD and CDH17 has antitumor activity and improved tumor specificity

Alyssa Synan, Nila C. Wu, Roberto Velazquez, Thomas G. Gesner, Claude Logel, Kathrin Mueller, Andrew R. Green, Patrizia Barzaghi-Rinaudo, Quincey Simmons, Samuele Mercan, Xingyi Shi, Xun Li, Vivek Sagar, Joshua M. Korn, Margaret E. McLaughlin, , Joseph A. D’Alessio

This study develops a bispecific antibody-drug conjugate targeting pCAD and CDH17, showing antitumor activity in dual antigen-expressing tumors but not in single antigen-expressing tumors.

mAbs · Jan 6, 2025Peer-reviewedCancer Biology