Author

Saravana Mohan Dhanasekaran

University of MichiganORCID 0000-0002-0489-2224Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Arul M. ChinnaiyaniD· 3 shared Xuhong CaoiD· 3 shared Hanbyul Cho· 2 shared Rahul MannaniD· 2 shared Sethuramasundaram PitchiayaiD· 2 shared Aaditya SinghiD· 1 shared Aniket DagariD· 1 shared Anna Pamela CalinawaniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

Arul M. ChinnaiyanORCID

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Author profile →

4 papers

Recent·Most cited

A harmonized single-cell RNA-seq atlas of human localized and metastatic prostate cancers and benign tissues

Hanbyul Cho, Yuping Zhang, Jiayi Zhou, Aniket Dagar, Sarah Kang, Rahul Mannan, Xuhong Cao, Saravana Mohan Dhanasekaran, Arul M. Chinnaiyan

This paper harmonizes single-cell RNA-seq data from 17 studies to create a comprehensive atlas of human prostate cancer and benign tissues, identifying 17 cell types and providing standardized resources for analysis.

bioRxiv · May 20, 2026 · PreprintCancer Biology

Dual-compartment engagement of STAR-family proteins SAM68 and QKI by LINC00941 sustains oncogenic fitness in RAS-driven lung cancer

Disha Acharya, Jean C-Y. Tien, Anu Sharma, Vinita Bhat, Aaditya Singh, Mohammad Azharuddin, Sethuramasundaram Pitchiaya, Xuhong Cao, Brendan A. Veeneman, Saravana Mohan Dhanasekaran, Balkrishna Chaube, Arul M. Chinnaiyan, Sudhanshu Shukla

This paper identifies LINC00941 as an oncogenic lncRNA regulated by FOSL1 in lung cancer, showing its dual-compartment role in sustaining tumor growth through SAM68 and QKI interactions.

bioRxiv · May 13, 2026 · PreprintCancer Biology

Cellular cartography reveals mouse prostate organization and determinants of castration resistance

Hanbyul Cho, Yuping Zhang, Jean Ching-Yi Tien, Rahul Mannan, Jie Luo, Sathiya Pandi Narayanan, Somnath Mahapatra, Jingzhou Hu, Greg Shelley, Gabriel Cruz, Miriam Shahine, Lisha Wang, Fengyun Su, Rui Wang, Xuhong Cao, , Arul M. Chinnaiyan

This study maps the mouse prostate's cellular organization and identifies key determinants of castration resistance using single-cell and spatial transcriptomics.

Proceedings of the National Academy of Sciences · Aug 25, 2025Peer-reviewedCancer Biology

ProTrack: An Interactive Multi-Omics Data Browser for Proteogenomic Studies

Anna Pamela Calinawan, Xiaoyu Song, Jiayi Ji, Saravana Mohan Dhanasekaran, Francesca Petralia, Pei Wang, Boris A. Reva

ProTrack provides an interactive web tool for exploring CPTAC proteogenomic data across multiple cancer types, enabling users to query and visualize multi-omics profiles without coding.

PROTEOMICS · Jun 8, 2020Peer-reviewedBioinformatics