Saashi A. Bedford

dGAMLSS: An exact, distributed algorithm to fit Generalized Additive Models for Location, Scale, and Shape for privacy-preserving population reference charts

The paper introduces dGAMLSS, a distributed algorithm for fitting GAMLSS models to construct population reference charts without sharing patient data.

Profiling brain morphology for autism spectrum disorder with two cross-culture large-scale consortia

This study identifies two ASD subgroups with distinct brain morphology using cross-cultural datasets, highlighting key brain regions associated with subgroup characteristics and autistic traits.

Charting structural brain asymmetry across the human lifespan

This paper presents a normative framework for brain asymmetry across the lifespan using a large neuroimaging dataset, revealing distinct spatial patterns and providing tools for clinical and research applications.

Joint signatures of morphological and microstructural inter-individual variation in the Alzheimer's spectrum

The paper identifies joint signatures of microstructural and morphological changes in the Alzheimer's spectrum using MRI metrics and non-negative matrix factorization, linking them to risk factors and disease progression.

A longitudinal resource for population neuroscience of school-age children and adolescents in China

The paper introduces a longitudinal dataset of school-age children and adolescents in China, detailing its design, sampling, and neuroimaging measurements.

High spatial overlap but diverging age-related trajectories of cortical MRI markers aiming to represent intracortical myelin and microstructure

The paper examines age-related trajectories of MRI cortical markers and finds high spatial overlap but divergent age trends, suggesting different microstructural origins for these markers.

Assessment of white matter hyperintensity severity using multimodal MRI in Alzheimer's Disease

This study assesses white matter hyperintensity severity using multimodal MRI in Alzheimer's Disease by analyzing signal measures from different MRI contrasts and their associations with clinical variables.

Variation in subcortical anatomy: relating interspecies differences, heritability, and brain-behavior relationships

The paper maps interspecies differences in subcortical anatomy between humans and chimpanzees, linking heritability, morphology, and behavioral correlates.

Brain charts for the human lifespan

The paper introduces brain charts as a standardized resource for benchmarking brain morphology across the human lifespan using MRI data from a large and diverse cohort.

Hippocampus shape across the healthy lifespan and its relationship with cognition

This study uses shape analysis to examine hippocampal changes across age and finds age-related shape changes linked to sex, education, and cognition.

Hippocampal subfield volumes across the healthy lifespan and the effects of MR sequence on estimates

The paper examines age-related changes in hippocampal subfield volumes across the lifespan and shows that MR sequence affects volumetric estimates.

Examining the boundary sharpness coefficient as an index of cortical microstructure and its relationship to age and sex in autism spectrum disorder

This study examines the boundary sharpness coefficient (BSC) as a measure of cortical microstructure in ASD, finding age, sex, and regional differences in BSC that correlate with clinical measures.