William Donald Hopkins

This study uses MRI and histopathology in squirrel monkeys to link R2* changes with CAA severity and ARIA-related tissue injury, supporting early detection and treatment strategies.

The paper identifies a distributed brain network associated with psychopathy in humans and chimpanzees, showing strong overlap with a lesion network linked to antisocial behavior.

The paper examines age-related changes in Alzheimer's disease biomarkers and their association with cortical atrophy in chimpanzees, finding significant correlations between biomarkers and brain aging phenotypes.

This study compares age-related changes in plasma neurodegeneration biomarkers between rhesus monkeys and baboons using a multiplex assay, finding species-specific patterns and associations with brain atrophy.

The paper compares the morphology of the caudal rami of the superior temporal sulcus across humans, chimpanzees, and other great apes using quantitative measurements.

This study identifies an arcuate fasciculus homolog in marmosets, showing convergent evolution with humans in connectivity patterns and vocalization-related brain activation.

The paper compares snRNA-seq data across species to identify cellular differences in the striatum, finding novel interneuron types in bats and differences in neuron-to-glia ratios between primates and non-primates.

The paper analyzes bulk RNA-seq data from six primate cerebellar subregions to identify gene expression differences across species, highlighting divergence in synaptic activity and glucose metabolism in lateral hemispheres.

The paper identifies a brain-wide twisting asymmetry in mice, similar to human cerebral petalia, using data from 3,500 animals across six cohorts.

This study computes sex-specific survival curves for 12 nonhuman primate species to characterize aging patterns and provides insights into lifespan and healthspan differences.

The paper compares age-related brain deterioration between humans and chimpanzees, finding a unique positive relationship between cerebral aging and cortical expansion in humans.

The paper builds a chimpanzee brain atlas and compares connectivity patterns between humans and chimpanzees, identifying genetic correlates of connectivity divergence.

This study uses single nucleus transcriptomics to compare human and non-human primate cortical tissues, identifying human-specific gene expression patterns and their potential functional roles.

The paper compares the morphology of Broca's areas between humans and chimpanzees, finding human-specific expansion in BA44 associated with syntax.

This study creates a new white matter connectivity atlas for chimpanzees and compares it to humans to understand primate brain evolution.

The paper examines age-related differences in gray matter covariation in baboons using source-based morphometry and finds significant age effects in specific brain regions.

The paper maps interspecies differences in subcortical anatomy between humans and chimpanzees, linking heritability, morphology, and behavioral correlates.

This study develops a chimpanzee brain reference template and processing pipeline to analyze structural MRI data, revealing age-related GM atrophy and hemispheric asymmetry patterns.

This study compares age-related changes in corpus callosum morphology between chimpanzees and humans, finding that human-specific atrophy occurs in old age.

This study identifies roles of frontal cortex regions in primate vocal production and their adaptation for human speech.

The paper examines sulcal morphology in the medial frontal cortex of primates to reveal evolutionary patterns and challenge previous assumptions about human uniqueness.