Author

Sneha Sudha Komath

Jawaharlal Nehru UniversityORCID 0000-0002-0491-7102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Harshita Saini· 2 shared Monika BharatiiD· 2 shared Shailja Shefali· 2 shared Yatin Kumar· 2 shared Aaisha Anzar· 1 shared Dip Shikha Maurya· 1 shared Faraz Mohd KhaniD· 1 shared Isaac Cherian· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Harshita Saini

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Author profile →

4 papers

Recent·Most cited

Purification and characterization of recombinant Rtt109, a fungus-specific histone acetyltransferase, from Candida albicans

Simran Sharma, Vijayan Ramachandran, Rohini Muthuswami, Samudrala Gourinath, Sneha Sudha Komath

This study characterizes the recombinant Rtt109 histone acetyltransferase from Candida albicans, identifies its functional requirements, and screens for potential inhibitors with clinical implications.

bioRxiv · Jul 30, 2026 · PreprintBiochemistry

Characterizing the endopeptidase activity of Candida albicans Gpi8, a crucial subunit of the GPI transamidase

Isaac Cherian, Shailja Shefali, Dip Shikha Maurya, Faraz Mohd Khan, Sneha Sudha Komath

This paper studies the endopeptidase activity of C. albicans Gpi8 using steady-state kinetics and molecular dynamics simulations to understand substrate binding and cleavage mechanisms.

bioRxiv · Apr 9, 2026 · PreprintBiochemistry

Arv1 interacts with and regulates the first step of GPI biosynthesis in Candida albicans

Monika Bharati, Harshita Saini, Neha Thakran, Yatin Kumar, Shailja Shefali, Shailja Shefali, Sunyna Saun, Aaisha Anzar, Sneha Sudha Komath

This study shows that Arv1 interacts with and regulates the first step of GPI biosynthesis in C. albicans through physical interaction and transcriptional control of GPI-GnT genes.

FEBS Journal · Aug 13, 2025Peer-reviewedMicrobiology

The ER-resident Ras Inhibitor 1 (Eri1) of Candida albicans inhibits hyphal morphogenesis via the Ras-independent cAMP-PKA pathway

Subhash Chandra Sethi, Monika Bharati, Yatin Kumar, Usha Yadav, Harshita Saini, Parvez Alam, Sneha Sudha Komath

This paper investigates the role of Eri1 in Candida albicans, showing it inhibits hyphal morphogenesis via a Ras-independent cAMP-PKA pathway and affects virulence.

ACS Infectious Diseases · Aug 9, 2024Peer-reviewedMicrobiology