Author

Erik D. Carlson

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Michael C. JewettiD· 3 shared Alexandra N. Ooms· 1 shared Ashty S. KarimiD· 1 shared Benjamin J. Des SoyeiD· 1 shared Brian R. Fritz· 1 shared Camila KofmaniD· 1 shared Daniel Eiler· 1 shared Daniel Herschlag· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersSynthetic Biology

Michael C. JewettORCID

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3 papers

Recent·Most cited

Improving genomically recoded Escherichia coli for the production of proteins containing non-canonical amino acids

Jessica G. Perez, Erik D. Carlson, Oliver Weisser, Camila Kofman, Kosuke Seki, Benjamin J. Des Soye, Ashty S. Karim, Michael C. Jewett

This paper improves genomically recoded E. coli strains for producing proteins with non-canonical amino acids by optimizing nuclease and protease function and introducing an inducible T7 RNA polymerase cassette.

bioRxiv · Dec 10, 2021 · PreprintSynthetic Biology

In vitro ribosome synthesis and evolution through ribosome display

Michael J. Hammerling, Brian R. Fritz, Danielle J. Yoesep, Do Soon Kim, Erik D. Carlson, Michael C. Jewett

This study develops an in vitro method for ribosome synthesis and evolution called RISE, demonstrating its ability to select for ribosome variants resistant to clindamycin and revealing positive epistasis in successful genotypes.

Nature Communications · Feb 28, 2020Peer-reviewedSynthetic Biology

Computational Design of Asymmetric Three-dimensional RNA Structures and Machines.

Joseph D. Yesselman, Daniel Eiler, Erik D. Carlson, Alexandra N. Ooms, Wipapat Kladwang, Xuesong Shi, David A. Costantino, Daniel Herschlag, Michael C. Jewett, Jeffrey S. Kieft, Rhiju Das

The paper introduces RNAMake, a tool for designing asymmetric RNA structures, validated through experimental methods and demonstrating successful creation of complex 3D RNA folds and synthetic ribosomes.

bioRxiv · Nov 21, 2017 · PreprintBioengineering