Author

Alexander Röntgen

University of CambridgeORCID 0000-0002-0500-4815Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Michele VendruscoloiD· 3 shared Christina E. ToomeyiD· 2 shared Joanne LachicaiD· 2 shared Sonia GandhiiD· 2 shared Zenon ToprakciogluiD· 2 shared Alfonso De SimoneiD· 1 shared Anna I. WernickiD· 1 shared Chun Wei PangiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiophysics

Michele VendruscoloORCID

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3 papers

Recent·Most cited

BiophysicsbioRxivPreprintSep 2, 2026

Melanin Suppresses Aβ Aggregation and Toxicity

Alexander Röntgen, Jan L Heise, Michele Vendruscolo, Zenon Toprakcioglu

This study shows melanin suppresses Aβ42 aggregation and toxicity in vitro and in a cell model, suggesting potential therapeutic applications for Alzheimer's disease.

DOI 10.64898/2026.09.01.748646

humanproteomics

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BiophysicsbioRxivPreprintJul 9, 2026

Low-abundance αSyn-112 promotes αSyn-140 aggregation in vitro and forms immunoreactive deposits in Parkinson's disease brain tissue

Alexander Röntgen, Giuliana Fusco, Jonathan C. Breiter…·Michele Vendruscolo

DOI 10.64898/2026.07.05.736591

humanproteomics

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NeurosciencebioRxivPreprintMay 30, 2024

The diversity of SNCA transcripts in neurons, and its impact on antisense oligonucleotide therapeutics

James R. Evans, Emil Karl Gustavsson, Ivan Doykov…·Sonia Gandhi

The paper identifies novel SNCA transcripts in human dopaminergic neurons and demonstrates their impact on antisense oligonucleotide therapy for Parkinson's disease.

9 citations

humanlong-read sequencing

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