Maria Carolina Elias

New Histone H4 variant and H2B variant Exhibits Distinct Genomic Locations, Chromatin Affinities, and Dynamics Throughout Life Cycle and Cell Cycle of Trypanosoma cruzi

This study identifies a novel histone H4 variant (H4.V) in Trypanosoma cruzi, showing distinct genomic localization, expression profiles, and chromatin-binding dynamics compared to H2B.V.

Stage-Specific MCM Protein Expression in Trypanosoma cruzi: Insights Into Metacyclogenesis and G1 Arrested epimastigotes.

This study examines MCM protein expression and localization in Trypanosoma cruzi during metacyclogenesis and G1 arrest, revealing their role in cell cycle regulation and replication arrest.

Unraveling Dengue Serotype 3 Transmission in Brazil: Evidence for Multiple Introductions of the 3III_B.3.2 Lineage

This study analyzes DENV-3 genomes in Brazil to identify multiple introductions of the 3III_B.3.2 lineage and trace its spread from the Caribbean and Costa Rica.

Comprehensive Molecular Epidemiology of Influenza Viruses in Brazil: Insights from a Nationwide Analysis

This study analyzes the molecular epidemiology of Influenza A and B viruses in Brazil from 2021 to 2023, revealing lineage dominance patterns and mutations that may impact vaccine efficacy.

Comprehensive Analysis of Nascent Transcriptome Reveals Diverse Transcriptional Profiles Across the Trypanosoma cruzi Genome Underlining the Regulatory Role of Genome Organization, Chromatin Status, and Cis-Acting Elements

The paper analyzes nascent transcriptomes of Trypanosoma cruzi to show asymmetric transcriptional abundance and links it to genome organization, chromatin status, and cis-acting elements.

Proposing a Systematic Lineage Classification Below the Genotype Level for Dengue Serotypes 1 and 2

The paper proposes a lineage classification system for Dengue serotypes 1 and 2 using complete genome sequences to improve tracking of viral diversity and public health interventions.

Genomic epidemiology reveals the impact of national and international restrictions measures on the SARS-CoV-2 epidemic in Brazil

The paper uses genomic data to analyze how national and international restrictions affected SARS-CoV-2 transmission in Brazil and Paraguay, showing the spread of variants and the role of importation.

Transcription activity contributes to the firing of non-constitutive origins in Trypanosoma brucei

The paper shows that transcription activity triggers non-constitutive origins in Trypanosoma brucei to ensure timely DNA replication.