Terry C. Burns

Functional genomics identifies therapeutic options, biomarkers, and resistance mechanisms for high-grade gliomas

This study identifies therapeutic options, biomarkers, and resistance mechanisms for high-grade gliomas using genomic, transcriptomic profiling, and drug testing in patient-derived models.

Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT

The paper introduces INSIGHT, a platform for phosphoproteomic analysis of rare cell subpopulations, and applies it to study signaling changes in disseminated glioblastoma cells in vivo.

CSF-Seq enables transcriptome-wide profiling of cerebrospinal fluid and identifies prognostic signature of leptomeningeal disease

CSF-Seq profiles cerebrospinal fluid transcriptomes to identify a prognostic gene signature for leptomeningeal disease.

Chromosome-arm-specific telomere length governs dual modes of structural genome evolution in IDH-mutant astrocytoma

This study uses long-read sequencing to show that telomere length differences between chromosome arms influence structural genome changes in IDH-mutant astrocytomas.

Systems analysis uncovers early temozolomide responses and peptide antigens in glioblastoma

This study uses a multi-omics approach to analyze early TMZ responses in GBM cells, identifying TMZ-associated peptide antigens and immune-related changes.