Author

Christian Gege

Heidelberg UniversityORCID 0000-0002-0512-2774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex OdermattiD· 1 shared Alexander C.-Y. Tsai· 1 shared Amit V. PandeyiD· 1 shared Birgit WaltenbergeriD· 1 shared Daniel P. CahilliD· 1 shared Daniel VittiD· 1 shared Daniela SchusteriD· 1 shared Diana D. ShiiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alex OdermattORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 17, 2026

KDM6 Enzymes are the Mechanistic Targets of Mutant IDH that Dictate Replication Stress Sensitivity

Alexander C.-Y. Tsai, Mathew D. Lin, Vineshkumar Thidil Puliyappadamba…·Diana D. Shi

This study identifies KDM6 enzymes as targets of R2HG from mutant IDH, linking them to replication stress sensitivity in gliomas and introduces a DHODH inhibitor, GLIO-1, with potential clinical applications.

DOI 10.64898/2026.04.14.715350

humanproteomics

𝕏 PostBluesky

BioinformaticsInternational Journal of Molecular SciencesPeer-reviewedSep 26, 2020

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

Fabian Mayr, Gabriele Möller, Ulrike Garscha…·Daniela Schuster

The paper develops an in silico workflow to predict molecular targets of natural products and identifies four new targets for dihydrochalcones.

36 citations

statistical modeldrug response / drug discovery

𝕏 PostBluesky