Tumour suppressor WT1 and its interacting protein RNA helicase DDX5 regulate the microRNA let7/Igf1r axis in the kidney mesenchyme
Sourav Dey, Joan Slight, Stuart Aitken…·Ruthrothaselvi Bharathavikru
The paper shows WT1 and DDX5 regulate the let7/Igf1r axis in kidney mesenchyme, linking WT1 mutations to Wilms Tumour through microRNA and IGF signalling pathways.