RNA Methylation dynamics regulates cancer stemness through modulation of cell migration and cell proliferation in the spheroidal model of TNBC
Sourav Dey, Swati Shree Padhi, Rashmi Ranjan Behera, Sangita Lala, MM Arshida, Priyanka Das, Ruthrotha Selvi Bharathavikru
This study investigates the role of m6A regulators WTAP and FTO in TNBC cell proliferation, migration, and stemness using 2D and 3D cultures, finding m6A modulates cell cycle and EMT markers and CSC markers.
bioRxiv · Jul 22, 2025 · PreprintCancer Biology