Crystal X. Wang

Synthesis-driven reverse metabolomics reveals 3-hydroxy N-acyl amides as gut microbial molecules

The paper synthesizes 3-hydroxy N-acyl amides and uses reverse metabolomics to identify their presence in biological samples and link them to microbial production and metabolic disease.

Serum metabolomics reveals signatures associated with physical resilience trajectories from middle to older age

The paper identifies metabolomic signatures associated with physical resilience trajectories from middle to older age using long-term serum data.

The Everything Bagel Feature Finder: Ultra-fast automated feature finding for untargeted metabolomics

The Everything Bagel feature finder automates metabolomics data processing, achieving comparable or better performance than existing methods with significantly reduced computational time.

Serum metabolic signatures of cognitive resilience in a longitudinal aging cohort

The paper identifies serum metabolic signatures associated with cognitive resilience in a longitudinal aging cohort using untargeted LC-MS/MS profiling.

Community Curation of Microbial Metabolites Enables Biological Insights of Metabolomics Data

The paper introduces a collaborative platform for curating microbial metabolite knowledge to enhance metabolomics data interpretation.

MS/MS Mass Spectrometry Filtering Tree for Bile Acid Isomer Annotation.

This paper introduces a mass spectrometry filtering tree to distinguish bile acid isomers in LC-MS/MS data and identifies a novel deoxycholyl-2-aminophenol amidate linked to whole grain consumption.

The microbiome diversifies N-acyl lipid pools - including short-chain fatty acid-derived compounds

The paper creates a spectral library of N-acyl lipids from metabolomics data, identifies novel compounds, and links them to health conditions like HIV and cognitive impairment.

Empirically establishing drug exposure records directly from untargeted metabolomics data

The paper develops a drug exposure resource from untargeted metabolomics data to identify medications without clinical records.