Author

Charles B. Reilly

Harvard UniversityORCID 0000-0002-0541-0741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:simulation· 1

Frequent Co-Authors

Donald E. IngberiD· 2 shared Sylvie G. BernieriD· 2 shared Austin Paul· 1 shared Benedetto MarelliiD· 1 shared Bogdan BudnikiD· 1 shared Emilia Javorsky· 1 shared Jeffrey C. WayiD· 1 shared Joel Moore· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiochemistry

Donald E. IngberORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Control of Molecular Biochemistry and Cell Injury Responses through Highly Ordered Supramolecular Assembly of Flavonoids

Charles B. Reilly, Sylvie G. Bernier, Sanjid Shahriar, Viktor Horváth, Michael Lewandowski, Emilia Javorsky, Bogdan Budnik, Donald E. Ingber

Molecular dynamic simulations reveal flavonoids self-assemble into ordered structures that interact with proteins, modulate enzyme activity, and protect cells from UV-induced injury.

Frontiers in Nutrition · Sep 2, 2025Peer-reviewedBiochemistry

Broad-Spectrum Coronavirus Inhibitors Discovered by Modeling Viral Fusion Dynamics

Charles B. Reilly, Joel Moore, Shanda L. Lightbown, Austin Paul, Sylvie G. Bernier, Kenneth E. Carlson, Donald E. Ingber

The paper identifies broad-spectrum coronavirus inhibitors using molecular dynamics and AI docking, showing efficacy against SARS-CoV-2 and related viruses in cell and mouse models.

Frontiers in Molecular Biosciences · May 15, 2025Peer-reviewedMicrobiology

Tardigrade secretory proteins protect biological structures from desiccation

Samuel Lim, Charles B. Reilly, Zeina Barghouti, Benedetto Marelli, Jeffrey C. Way, Pamela A. Silver

This study investigates SAHS proteins from tardigrades, showing they protect biological structures from desiccation by preventing liposome fusion and enhancing microbial survival.

Communications Biology · May 25, 2024Peer-reviewedMolecular Biology