Pradeep Gautam

Deciphering tumour microenvironment and elucidating the origin of cancer cells in ovarian clear cell carcinoma

This study uses scRNA-seq to analyze the tumor microenvironment and cell types in ovarian clear cell carcinoma, identifying immune infiltration and similarities with endometriosis.

Potential modes of COVID-19 transmission from human eye revealed by single-cell atlas

The paper identifies conjunctival cells as potential entry points for SARS-CoV-2 by showing they express both ACE2 and TMPRSS2 receptors.

Diversification of Reprogramming Trajectories Revealed by Parallel Single-cell Transcriptome and Chromatin Accessibility Sequencing

This study uses scRNA-Seq and scATAC-Seq to show that human reprogramming occurs through asynchronous, diverse trajectories with distinct regulatory networks.

Parallel Bimodal Single-cell Sequencing of Transcriptome and Chromatin Accessibility

The paper introduces ASTAR-Seq, a method for parallel single-cell transcriptome and chromatin accessibility sequencing, and uses it to analyze mESCs, human cell lines, and erythroblast differentiation.

Insights into regeneration from the genome, transcriptome and metagenome analysis of Eisenia fetida

The paper presents genome, transcriptome, and metagenome data from Eisenia fetida to study regeneration dynamics, identifying differentially expressed genes and microbial communities.