Deborah M. Hegarty

Perineuronal nets in the rat medial prefrontal cortex alter hippocampal-prefrontal oscillations and reshape cocaine self-administration memories

This study shows that removing perineuronal nets in the rat medial prefrontal cortex reduces cocaine self-administration memory acquisition and disrupts reconsolidation when combined with novel reactivation.

Resveratrol increases tear production and spontaneous ocular pain after corneal abrasion in male, but not female, rats using a preclinical model of photorefractive keratectomy (PRK)

This study develops a preclinical PRK model in rats to evaluate resveratrol's effect on ocular pain and tear production, finding sex-specific outcomes.

Diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex

The paper examines diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex, finding increased PNN and PV staining intensity during the dark phase.

Cocaine memory reactivation induces functional adaptations of fast-spiking interneurons in the rat medial prefrontal cortex

This study shows that cocaine memory reactivation reduces PV intensity and alters electrophysiological properties of PV FSIs in the rat medial prefrontal cortex.

Acute Hyperalgesia and Delayed Dry Eye After Corneal Abrasion Injury

This study investigates the temporal dynamics of pain, lacrimation, and corneal nerve changes after corneal abrasion in rats, finding distinct molecular responses in trigeminal ganglia and peripheral endings.