Haojie Yu

This paper demonstrates chemically programmed multistage morphogenesis in coacervate microdroplets using oxidation reactions and enzyme pathways to drive structural changes and fluorescent signaling.

This paper develops a high-quality, scalable workflow for whole-cell single-cell RNA sequencing of adult cardiomyocytes and non-myocytes using in-cell ligation and split-pool barcoding, improving data quality and throughput.

CanASM identifies and annotates allele-specific DNA methylation in 31 cancer types, providing regulatory annotations and tools for analyzing epigenetic regulation in cancer.

This study identifies 21 genes whose rare variants affect LDL-C levels by altering cholesterol uptake, using CRISPR screening and co-essentiality analysis.

The paper introduces eccDB, a database that integrates eccDNA data across four species and provides analysis of eccDNA-chromosome interactions and regulatory features.