Teun P. de Boer

CardioShift resolves cell-to-cell functional heterogeneity in hiPSC-derived cardiomyocytes by accounting for nested variance, revealing hidden subpopulations and condition-dependent phenotypes.

This study identifies a zebrafish-specific gene regulatory network where Isl1 restricts Nkx2-5 to maintain pacemaker identity, distinct from mammalian mechanisms.

This paper develops a computational model to identify and correct artefacts in voltage-clamp experiments, improving the accuracy of ion channel recordings.

This study identifies mitochondrial and metabolic disturbances in sensory neurons as key factors in the transition from acute to chronic pain following inflammation.

The paper quantifies cardiomyocyte regeneration in zebrafish after injury, finding complete numerical replacement but incomplete differentiation and scar resorption.