This study investigates the virological features of SARS-CoV-2 Omicron XBB.1.9 subvariants, finding increased pathogenicity and transmissibility in HK.3 and EG.5.1 compared to previous variants.

Journal of Virology · Nov 18, 2025Peer-reviewedMicrobiology

SARS-CoV-2 JN.1 reveals attenuated pathogenicity and airborne transmission

Ruixue Liu, Qiushi Jin, Wenqi Wang, Cheng Zhang, Hang Zhang, Bing Li, Yan Fang, Xianzhu Xia, Jianmin Li, Xuefeng Wang, Yuwei Gao

This study shows that SARS-CoV-2 JN.1 has reduced pathogenicity and airborne transmission compared to previous variants.

bioRxiv · Nov 7, 2024 · PreprintMicrobiology

Virological characteristics of SARS-CoV-2 Omicron BA.5.2.48

Wenqi Wang, Qiushi Jin, Ruixue Liu, Wentao Zeng, Pengfei Zhu, Tingting Li, Tiecheng Wang, Haiyang Xiang, Hang Zhang, Qin Chen, Yun Jie Gao, Yana Lai, Yan Fang, Xianzhu Xia, Jianmin Li, , Yuwei Gao

This study evaluates the virological characteristics of BA.5.2.48 subvariant isolates, finding enhanced transmission and pathogenicity compared to BA.2, with divergent features among subvariants.

Frontiers in Immunology · Oct 1, 2024Peer-reviewedMicrobiology

piRNA pathway is essential for generating functional oocytes in golden hamster

Hongdao Zhang, Fengjuan Zhang, Qinghua Chen, Mingzhe Li, Xiaolong Lv, Yali Xiao, Zhaozhen Zhang, Li Hou, Yana Lai, Ying Zhang, Aihua Zhang, Shiqi Gao, Heling Fu, Wen Xiao, Jianli Zhou, , Jianmin Li

This study shows that piRNAs are essential for generating functional oocytes in golden hamsters, with defects leading to sterility and embryonic arrest.

Nature Cell Biology · Sep 1, 2021Peer-reviewedDevelopmental Biology