Author

Zhaozhen Zhang

Fudan University Shanghai Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aihua ZhangiD· 1 shared Aimin ShiiD· 1 shared Dashan AiiD· 1 shared Fei DingiD· 1 shared Feiyang DiaoiD· 1 shared Fengjuan ZhangiD· 1 shared Han LiangiD· 1 shared Hao ZhuiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Aihua ZhangORCID

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2 papers

Recent·Most cited

NRF2 pathway activation and SPP1⁺TREM2⁺ macrophages drive chemoradiotherapy resistance in esophageal squamous cell carcinoma

Jiaying Deng, Zhenzhen Xun, Hu Chen, Yanhong Cen, Yikai Luo, Wei Liu, Weiwei Chen, Junqiang Chen, Jinjun Ye, Xiansu Gao, Qingsong Fan, Jibin Song, Qi Chen, Yuan Li, Fei Ding, , Han Liang

This study identifies NRF2 pathway activation and SPP1⁺TREM2⁺ macrophages as drivers of chemoradiotherapy resistance in ESCC through multi-omics analysis of clinical trial data.

bioRxiv · Feb 21, 2026 · PreprintCancer Biology

piRNA pathway is essential for generating functional oocytes in golden hamster

Hongdao Zhang, Fengjuan Zhang, Qinghua Chen, Mingzhe Li, Xiaolong Lv, Yali Xiao, Zhaozhen Zhang, Li Hou, Yana Lai, Ying Zhang, Aihua Zhang, Shiqi Gao, Heling Fu, Wen Xiao, Jianli Zhou, , Jianmin Li

This study shows that piRNAs are essential for generating functional oocytes in golden hamsters, with defects leading to sterility and embryonic arrest.

Nature Cell Biology · Sep 1, 2021Peer-reviewedDevelopmental Biology