Author

Walaa E. Kattan

Broad InstituteORCID 0000-0002-0599-9744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:imaging· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alex K. ShalekiD· 1 shared Benjamin E. MeadiD· 1 shared Brian ClearyiD· 1 shared Bryan D. BrysoniD· 1 shared Christian K. SouleiD· 1 shared Conner KummerloweiD· 1 shared Haoqiang YingiD· 1 shared Hong LiangiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Alex K. ShalekORCID

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2 papers

Recent·Most cited

Nanoclustering and signaling of KRAS G12C and KRAS G12D respond to lipid acyl chain remodeling in an allele-specific manner

Neha Arora, Hong Liang, Walaa E. Kattan, Wantong Yao, Haoqiang Ying, J. Liu, Yong Zhou

This study shows that KRAS G12C and G12D mutants respond differently to lipid acyl chain remodeling, affecting their nanoclustering and signaling activities.

Journal of Lipid Research · Jun 16, 2026Peer-reviewedCancer Biology

Compressed phenotypic screens for complex multicellular models and high-content assays

Benjamin E. Mead, Conner Kummerlowe, Nuo Liu, Walaa E. Kattan, Thomas Cheng, Jaime H. Cheah, Christian K. Soule, Josh Peters, Kristen E. Lowder, Paul C. Blainey, William C. Hahn, Brian Cleary, Bryan D. Bryson, Peter S. Winter, Srivatsan Raghavan, Alex K. Shalek

The paper introduces a method to compress phenotypic screens using computational deconvolution, demonstrating increased efficiency and applicability to complex multicellular models.

bioRxiv · Jan 23, 2023 · PreprintSystems Biology