Author
The University of Texas Health Science Center at HoustonORCID 0000-0001-9198-8744Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Neha Arora, Rafael Bravo, Hong Liang…·Yong Zhou
This study shows that lipid acyl chain remodeling via LPCAT3 affects KRAS nanoclustering and oncogenic activity by altering membrane composition.
Neha Arora, Hong Liang, Walaa E. Kattan…·Yong Zhou
This study shows that KRAS G12C and G12D mutants respond differently to lipid acyl chain remodeling, affecting their nanoclustering and signaling activities.
Wenzhe Chen, George E. Maio, Xiao Chen…·Hening Lin
This study identifies DHHC7 as a palmitoyl transferase that modifies KRAS4A, enhancing its membrane localization and activation, and shows that targeting DHHC7 inhibits pancreatic tumor growth.
Neha Arora, Liang Hong, Yong Zhou
The paper shows that RAS G-domains influence the sorting of phosphatidylserine acyl chains in the plasma membrane, with different mutants sorting distinct PS species.