Mie Monti

Host tRNA modifications drive efficient translation of influenza A virus genome and impact host antiviral stress responses

The paper shows that host tRNA modifications are critical for efficient influenza A virus translation and antiviral responses, with ELP3 loss impairing viral propagation.

Selective profiling of translationally active tRNAs and their dynamics under stress

The paper introduces tRIBO-seq, a nanopore-based method to profile ribosome-associated tRNAs, revealing stress-induced changes in tRNA abundance, modification, and fragmentation.

Benchmarking tRNA-Seq quantification approaches by realistic tRNA-Seq data simulation identifies two novel approaches with higher accuracy

The paper benchmarks tRNA-Seq quantification methods using simulated data, identifying two novel approaches with higher accuracy than existing methods.

Unbiased dynamic characterization of RNA-protein interactions by OOPS

The paper introduces OOPS, a method to enrich RNA-binding proteins and RNA, enabling unbiased analysis of RNA-protein interactions in dynamic systems and identifying novel RBPs.