Kira Kerkhoff

Harmonized nucleoside mass spectrometry enables reproducible cross-platform RNA modification quantification

The paper benchmarks cross-platform RNA modification quantification using LC-MS/MS and finds that harmonized workflows and SILIS normalization improve reproducibility across different instrument types.

Human 28S rRNA analysed by state-of-the-art oligonucleotide mass spectrometry: benchmarking current capabilities and a call to action for MS-Seq

The paper benchmarks MS-Seq for human 28S rRNA analysis, showing reproducible results across platforms but highlighting gaps in coverage and ambiguity.

Long-term stability of RNA nucleoside standards for accurate LC-MS quantification

This study evaluates the long-term stability of RNA nucleoside standards under different storage conditions and proposes guidelines for their preparation and quality control.

Host tRNA modifications drive efficient translation of influenza A virus genome and impact host antiviral stress responses

The paper shows that host tRNA modifications are critical for efficient influenza A virus translation and antiviral responses, with ELP3 loss impairing viral propagation.