Ana Raquel Soares

The paper shows that host tRNA modifications are critical for efficient influenza A virus translation and antiviral responses, with ELP3 loss impairing viral propagation.

The paper introduces tRIBO-seq, a nanopore-based method to profile ribosome-associated tRNAs, revealing stress-induced changes in tRNA abundance, modification, and fragmentation.

The paper integrates differential gene expression with WGCNA to identify aging-related expression signatures in mouse tissues, revealing common proteostasis pathways across multiple organs.

The paper shows that mutations in tRNA-modifying enzymes in yeast lead to mistranslation and protein aggregation by affecting specific tRNA modifications.