Xiaozhen Wen

Sequence Generation and Phylogenetic Inference with Generative Flow Networks

This paper introduces AncestorGFN, a method using Generative Flow Networks for alignment-free sequence generation and phylogenetic inference, showing it can recover ancestral relationships and generate novel sequences.

RAFTER: a releasing factor tethered RNA editing system for quantifying mRNA translation

RAFTER quantifies mRNA translation by labeling efficiently translated RNAs with an RNA editing enzyme and releasing factor, showing correlation with Ribo-seq and Polysome-seq but with a simpler workflow enabling single-cell analysis.