Author
University of California, Santa BarbaraORCID 0000-0002-0618-6390Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Sofia Gotthold, Keile R. Hansen, Andrew N. Brown…·Chris D. Richardson
This study identifies SFPQ as a factor promoting homologous recombination by stabilizing RAD51 and its paralogs' mRNA, independent of DSB localization or p53 activation.
Christine M. Joyce, Julien Bacal, Soham P. Chowdhury…·Chris D. Richardson
This study identifies FANCD2-FANCI's role in coordinating chromatin openness and cell cycle arrest during DNA double-strand break repair.
Connor J. Sheedy, Soham P. Chowdhury, Bashir A. Ali…·Brooke M. Gardner
This study shows that the PEX1G843D mutation impairs PEX1/PEX6 assembly and leads to proteasomal degradation, but overexpression can restore peroxisome function.
Jonathan T. Vu, Katherine U. Tavasoli, Connor J. Sheedy…·Brooke M. Gardner
The paper identifies RNF146 and tankyrase as regulators of peroxisome function and links them to Wnt signaling through their role in PARsylation and beta-catenin degradation.
Hannah I. Ghasemi, Julien Bacal, Amanda J. Yoon…·Chris D. Richardson
The paper shows that interstrand crosslinked DNA templates (xHDRTs) significantly boost gene editing efficiency in human cells by up to five-fold, independent of template topology or cell type.