Philippe Isope

Subthreshold violations of trajectory predictions are sensitive to TMS of Cerebellum CRUS I/II

The paper investigates how transcranial magnetic stimulation (TMS) of the cerebellum affects trajectory prediction errors and their neural correlates using an illusion-based paradigm.

Medial prefrontal cortex encodes implicit temporal expectations in mice

This study investigates how medial prefrontal cortex encodes implicit temporal expectations in mice and shows cerebellar input influences these predictions.

Excitation and inhibition delays within a feedforward inhibitory pathway modulate cerebellar Purkinje cell output in mice

The paper investigates how excitation and inhibition delays in cerebellar Purkinje cells modulate output through a feedforward inhibitory pathway in mice.

Cerebellar connectivity maps embody individual adaptive behavior

The paper shows that cerebellar connectivity maps in mice vary with locomotor conditions and correlate with individual behavioral features.

Lumbar corticospinal tract in rodents modulates sensory inputs but does not convey motor command

This study shows that in mice, the lumbar corticospinal tract primarily modulates sensory inputs through interneurons rather than conveying motor commands.

SUSD4 controls GLUA2 degradation, synaptic plasticity and motor learning

This study identifies SUSD4 as a regulator of GLUA2 degradation and synaptic plasticity, showing its role in motor learning and implications for neurodevelopmental diseases.

Gradients in the cerebellar cortex enable Fourier-like transformation and improve storing capacity

The paper identifies biophysical gradients in cerebellar granule cells that enable Fourier-like transformation of mossy fiber inputs and enhance spike-timing precision.

Molecular and functional heterogeneity of cerebellar granule cell terminals expands temporal coding in molecular layer interneurons.

The paper shows that molecular diversity in cerebellar granule cell terminals leads to different temporal coding in molecular layer interneurons.

A frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity

The paper demonstrates frequency-dependent mobilization of synaptic vesicle sub-pools in cerebellar synapses, showing how different sub-pools are recruited based on stimulation frequency to shape presynaptic plasticity.