Charlotte Bichara

Electrophysiological signatures reveal spinal learning mechanisms for a lasting sensorimotor adaptation

The paper identifies spinal inhibitory interneurons involved in sensorimotor adaptation through electrophysiological recordings and behavioral analysis in mice.

Lumbar corticospinal tract in rodents modulates sensory inputs but does not convey motor command

This study shows that in mice, the lumbar corticospinal tract primarily modulates sensory inputs through interneurons rather than conveying motor commands.

Enhanced analgesic cholinergic tone after neuropathy

The paper shows that increasing spinal acetylcholine levels through low-dose AChE inhibitors reduces mechanical allodynia in neuropathic mice.

Absence of subcerebral projection neurons delays disease onset and extends survival in a mouse model of ALS

This study shows that removing subcerebral projection neurons in ALS mice delays disease onset and improves survival, supporting the corticofugal hypothesis of ALS.