Hartmut Schmidt

The paper identifies differences in synaptic nanoarchitectures between prefrontal and somatosensory cortices, linking loose coupling to higher order brain functions.

The paper develops transgenic mouse lines with red fluorescent labeling of myelin, enabling structural and functional imaging compatible with green spectral sensors.

The paper compares synaptic properties of pyramidal neurons in M2 to those in M1 and PFC, finding M2 synapses exhibit intermediate characteristics between the two.

The paper proposes a framework to identify the presence of a series-connected replacement pool in synaptic vesicle dynamics using electrophysiological methods.

The paper measures the Ca2+ sensitivity of Syt1-triggered release in neocortical synapses and finds it has high affinity and cooperativity.

This study shows that LTP at layer 5 pyramidal neurons increases synaptic strength by increasing the number of fully-primed, slowly-recovering vesicles.

The paper investigates Ca2+-dependence of synaptic vesicle recruitment, priming, and fusion at cerebellar mossy fiber synapses, revealing distinct Ca2+ sensors for each step.

The paper demonstrates frequency-dependent mobilization of synaptic vesicle sub-pools in cerebellar synapses, showing how different sub-pools are recruited based on stimulation frequency to shape presynaptic plasticity.