Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells
Eloïse M. Grasset, Atul M. Deshpande, Jae Woo Lee, Yeonju Cho, Sarah M. Shin, Erin M. Coyne, Alexei Hernandez, Xuan Yuan, Zhehao Zhang, Ashley Cimino‐Mathews, Andrew J. Ewald, Won Jin Ho
The paper uses spatial analysis to show metastasis-initiating cancer cells in breast tumors are closely associated with specific macrophage subtypes, suggesting these interactions promote metastasis.
Oncogene · Aug 20, 2024Peer-reviewedCancer Biology