A tumour-host feed-forward loop contributes to malignant growth in chromosomal instability-induced epithelial tumours
Kaustuv Ghosh, Aishwarya Kunchur, Marco Milán
The paper shows that aneuploidy-induced senescent cells in Drosophila tumours secrete proteins that promote non-autonomous cell death, which in turn enhances tumour growth through feedback mechanisms.
EMBO Reports · Jun 5, 2026Peer-reviewedCancer Biology