Author

Alex Gileles‐Hillel

Hebrew University of JerusalemORCID 0000-0002-0656-905XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1

Frequent Co-Authors

David GozaliD· 2 shared Abdelnaby Khalyfa· 1 shared Amelia Cox· 1 shared Cayleigh Wallace· 1 shared Hong YueiD· 1 shared John P. DriveriD· 1 shared Minhui GuaniD· 1 shared Moran Li· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

David GozalORCID

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2 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedApr 21, 2026

Poor sleep impairs immune responses and influenza vaccine protection

Minhui Guan, Weihong Gu, Alex Gileles‐Hillel…·Xiu‐Feng Wan

Poor sleep weakens both the magnitude and quality of immune responses, compromising the protective efficacy of influenza vaccination.

1 citation

mousebulk RNA-seq

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Cell BiologybioRxivPreprintDec 15, 2025

Thymidine Phosphorylase Drives SARS-CoV-2 Spike Protein-Induced Lung Tumorigenesis

Cayleigh Wallace, Alex Gileles‐Hillel, Amelia Cox…·Hong Yue

This study shows that SARS-CoV-2 Spike protein promotes lung tumorigenesis via TYMP-dependent mechanisms, increasing lung cancer risk in COVID-19 survivors, especially smokers.

DOI 10.64898/2025.12.14.694192

mouseclinical cohort / trial

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