Author

Joachim Jose

University of MünsterORCID 0000-0002-0666-2676Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

Alexander GastiD· 1 shared Andreas LangeiD· 1 shared Barbara Lecis· 1 shared Bernard D. G. EeninkiD· 1 shared Bert van LooiD· 1 shared Carina Dilkaute· 1 shared Chun-Lei ZhangiD· 1 shared Demetra Ballardin· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Alexander GastORCID

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2 papers

Recent·Most cited

Studying the evolutionary potential of ancestral aryl sulfatases in the alkaline phosphatase family with droplet microfluidics

Bernard D. G. Eenink, Josephin Marie Holstein, Magdalena Heberlein, Carina Dilkaute, Joachim Jose, Florian Hollfelder, Bert van Loo, Erich Bornberg‐Bauer, Tomasz S. Kamiński, Andreas Lange

The paper uses droplet microfluidics to study the evolvability and robustness of ancestral and extant aryl sulfatases under varying mutation rates.

The Analyst · Jan 1, 2026Peer-reviewedEvolutionary Biology

Missense mutation in the activation segment of the kinase CK2 models Okur Chung neurodevelopmental disorder and alters the hippocampal glutamatergic synapse

Jose Manuel Cruz-Gamero, Demetra Ballardin, Barbara Lecis, Chun-Lei Zhang, Laetitia Cobret, Alexander Gast, Séverine Morisset‐Lopez, Rebecca A. Piskorowski, Dominique Langui, Joachim Jose, Guillaume Chevreux, Heike Rebholz

This paper creates a knockin mouse model with a K198R mutation in CK2 kinase, showing ASD-like behaviors and synaptic deficits, validating it as a model for Okur-Chung Neurodevelopmental Syndrome.

Molecular Psychiatry · Oct 4, 2024Peer-reviewedNeuroscience