Dominique Langui

This study shows that dural venous stenoses impair lymphatic drainage and brain fluid clearance, and that restoring venous flow can improve clearance in a mouse model.

This paper creates a knockin mouse model with a K198R mutation in CK2 kinase, showing ASD-like behaviors and synaptic deficits, validating it as a model for Okur-Chung Neurodevelopmental Syndrome.

This study investigates the role of APPL, the Drosophila homologue of APP, in neuronal survival and neuro-glial interactions, revealing its involvement in endolysosomal function and neuronal debris clearance.

This study identifies Vangl2 as a regulator of MuSK signaling in neuromuscular synapse formation, showing its role in AChR accumulation and NMJ stability.

The paper shows that Reissner fiber is critical for CSF-contacting neurons to detect spinal curvature in zebrafish larvae.