E Lezi

This study identifies NLP-12 as a neuropeptide that preserves neuronal structure and function in C. elegans by preventing excessive dendritic branching and maintaining proprioceptive ability during aging.

This study identifies LOAD risk gene homologs in C. elegans that modulate neuronal aging selectively in specific neuron classes, independent of lifespan, and highlights early endosomal and lipid pathways.

This study shows that reduced collagen in non-neuronal tissues drives specific aging-related changes in sensory neurons, independent of collagen's structural role.