Molecular BiologyGenome biologyPeer-reviewed
Simultaneous Epigenetic Perturbation and Genome Imaging Reveal Distinct Roles of H3K9me3 in Chromatin Architecture and Transcription
Ying Feng, Yao Wang, Xiangnan Wang…·Hanhui Ma
This study uses EpiGo-KRAB to introduce H3K9me3 at specific loci and shows it forms heterochromatin-like domains without widespread gene repression.