Danat Yermakovich

The paper identifies gene-environment interaction loci showing signs of selection and diet-dependent genetic effects across human populations.

The paper uses a massively parallel reporter assay to study the regulatory effects of variant pairs in enhancers, finding non-additive effects and context-dependent interactions.

The paper uses sequence-to-function models to predict the functional impact of archaic hominin introgression in Papuan individuals, identifying genes associated with introgressed haplotypes.

The paper investigates the regulatory effects of Neanderthal and Denisovan introgression in Papuan populations using a massively parallel reporter assay, finding differential activity in immune-related genes.

This study examines Denisovan and Neandertal DNA distribution in Papua New Guinean populations, finding that Denisovan-like haplotypes are associated with brain development and immune response genes, suggesting adaptive significance.

This study identifies Neandertal DNA's long-range regulatory effects on gene expression in modern humans, showing their influence on immune traits, schizophrenia, and other phenotypes.