Author

Patrice D. Smith

Carleton UniversityORCID 0000-0002-0731-2803Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Amanda C. Barber· 1 shared Amy R MacQueen· 1 shared Andrew OsborneiD· 1 shared Barbara HaenziiD· 1 shared Bart NieuwenhuisiD· 1 shared Britta Johanna EickholtiD· 1 shared Charles ffrench‐ConstantiD· 1 shared Craig S. PearsoniD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Amanda C. Barber

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS

Bart Nieuwenhuis, Amanda C. Barber, Rachel S Evans, Craig S. Pearson, Joachim Fuchs, Amy R MacQueen, Susan van Erp, Barbara Haenzi, Lianne A. Hulshof, Andrew Osborne, Raquel Conceição, Tasneem Z. Khatib, Sarita S. Deshpande, Joshua Cave, Charles ffrench‐Constant, , Richard Eva

The paper identifies axonal PIP3 deficiency as a cause of CNS regeneration failure and shows that p110δ can restore regeneration by acting hyperactively.

EMBO Molecular Medicine · Jun 17, 2020Peer-reviewedNeuroscience

Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice

Jamie E. Abato, Mahira Moftah, Greg O. Cron, Patrice D. Smith, Nafisa M. Jadavji

This study investigates how MTHFR deficiency in mice affects cellular responses after ischemic stroke, finding increased antioxidant activity and altered MAT2A and HIF-1 levels.

Nutritional Neuroscience · May 25, 2020Peer-reviewedNeuroscience