Author

Rachel S Evans

AstraZeneca (United Kingdom)ORCID 0000-0001-9647-1306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:rat· 1

Frequent Co-Authors

Alaide MorcavalloiD· 1 shared Amanda C. Barber· 1 shared Amy R MacQueen· 1 shared Andrew OsborneiD· 1 shared Anna Dominika StaniszewskaiD· 1 shared Anna Louise Beckett· 1 shared Barbara HaenziiD· 1 shared Bart NieuwenhuisiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alaide MorcavalloORCID

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2 papers

Recent·Most cited

Cancer BiologyCancersPeer-reviewedJan 20, 2026

An inducible BRCA1 expression system with in vivo applicability uncovers activity of the combination of ATR and PARP inhibitors to overcome therapy resistance

Elsa Irving, Alaide Morcavallo, Jekaterina Vohhodina-Tretjakova…·Josep V. Forment

This paper develops an inducible BRCA1 expression system to study hypomorphic variants and finds that combining ATR and PARP inhibitors overcomes resistance caused by BRCA1 {Delta}exon11 hypomorphs.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceEMBO Molecular MedicinePeer-reviewedJun 17, 2020

PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS

Bart Nieuwenhuis, Amanda C. Barber, Rachel S Evans…·Richard Eva

The paper identifies axonal PIP3 deficiency as a cause of CNS regeneration failure and shows that p110δ can restore regeneration by acting hyperactively.

56 citations

rathuman

𝕏 PostBluesky