Author

Andrew Osborne

University of CambridgeORCID 0000-0002-5649-2337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Bart NieuwenhuisiD· 2 shared Adolfo AmiciiD· 1 shared Amanda C. Barber· 1 shared Amy R MacQueen· 1 shared Andrea LoretoiD· 1 shared Barbara HaenziiD· 1 shared Boštjan KobeiD· 1 shared Britta Johanna EickholtiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Bart NieuwenhuisORCID

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2 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedDec 6, 2021

Potent activation of SARM1 by NMN analogue VMN underlies vacor neurotoxicity

Andrea Loreto, Carlo Angeletti, Weixi Gu…·Michael P. Coleman

This study identifies VMN, a metabolite of the pesticide vacor, as a potent SARM1 activator, showing that SARM1 removal rescues vacor-induced neuron and axon death.

70 citations

Drosophilaexperimental assay

𝕏 PostBluesky

NeuroscienceEMBO Molecular MedicinePeer-reviewedJun 17, 2020

PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS

Bart Nieuwenhuis, Amanda C. Barber, Rachel S Evans…·Richard Eva

The paper identifies axonal PIP3 deficiency as a cause of CNS regeneration failure and shows that p110δ can restore regeneration by acting hyperactively.

56 citations

rathuman

𝕏 PostBluesky