Author

Melanie R. Silvis

University of California, San FranciscoORCID 0000-0002-0732-9744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Byoung‐Mo KooiD· 1 shared Cameron C. Hearne· 1 shared Carol A. GrossiD· 1 shared Hendrik OsadnikiD· 1 shared Horia TodoriD· 1 shared Jason M. PetersiD· 1 shared John S. Hawkins· 1 shared Jonathan S. WeissmaniD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperSystems Biology

Byoung‐Mo KooORCID

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1 paper

Recent·Most cited

Modulated efficacy CRISPRi reveals evolutionary conservation of essential gene expression-fitness relationships in bacteria

John S. Hawkins, Melanie R. Silvis, Byoung‐Mo Koo, Jason M. Peters, Hendrik Osadnik, Marco Jost, Cameron C. Hearne, Jonathan S. Weissman, Horia Todor, Carol A. Gross

The paper develops a CRISPRi system to modulate gene expression in bacteria and shows that essential gene expression-fitness relationships are conserved across species.

Cell Systems · Oct 19, 2020Peer-reviewedSystems Biology