Author

Jiří Klempíř

Charles UniversityORCID 0000-0002-0735-7155Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Nazlı BaşakiD· 1 shared Åsa PeterséniD· 1 shared Chris KayiD· 1 shared Glen Lester SequieraiD· 1 shared Hailey Findlay BlackiD· 1 shared Huu Phuc NguyeniD· 1 shared Indhu‐Shree Rajan‐BabuiD· 1 shared Jessica DawsoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

A. Nazlı BaşakORCID

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1 paper

Recent·Most cited

Synonymous HTT CAA/CCA-loss variants associated with early Huntington disease onset enhance toxicity beyond somatic instability

Glen Lester Sequiera, Sophia C. Gjervan, Ryan T. McCallum, Jia Feng, Oguz K. Ozgoren, Sofia Bergh, Jocelyn Bégin, Jessica Dawson, Hailey Findlay Black, Chris Kay, Tanushri Soomarooah, Larissa Arning, Indhu‐Shree Rajan‐Babu, A. Nazlı Başak, Jiří Klempíř, , Mahmoud A. Pouladi

This study shows that HTT CAA/CCA-loss variants increase toxicity in Huntington disease models independently of somatic repeat instability.

bioRxiv · Sep 8, 2026 · PreprintGenetics