Author

Ashley C. Humphries

Icahn School of Medicine at Mount SinaiORCID 0000-0002-0737-801XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

C. Clayton Hazelett· 1 shared Claudia Molina-PelayoiD· 1 shared Danelle DevenportiD· 1 shared Marek MlodzikiD· 1 shared Parijat SiliD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperDevelopmental Biology

C. Clayton Hazelett

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1 paper

Recent·Most cited

Developmental BiologyPLoS GeneticsPeer-reviewedJul 18, 2023

A Van Gogh/Vangl tyrosine phosphorylation switch regulates its interaction with core Planar Cell Polarity factors Prickle and Dishevelled

Ashley C. Humphries, Claudia Molina-Pelayo, Parijat Sil…·Marek Mlodzik

The paper shows that phosphorylation of a specific tyrosine in Vang/Vangl regulates its interaction with Pk and Dsh/Dvl, promoting the formation of the Vang/Vangl-Pk complex during PCP establishment.

27 citations

Drosophilamouse

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