Dishevelled-mediated clustering stabilizes Frizzled6 and Vangl2 to establish planar cell polarity in the mammalian skin
Parijat Sil, Brandon M. Trejo, Katherine A. Little, Danelle Devenport
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Princeton UniversityORCID 0000-0002-8391-8110Unclaimed ORCID profile · follow to get notified of new preprints
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4 papers
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Parijat Sil, Brandon M. Trejo, Katherine A. Little, Danelle Devenport
Parijat Sil, Thomas S. van Zanten, Sowmya Jahnavi…·Satyajit Mayor
The paper shows that two classes of myosins organize distinct membrane domains through active forces, enabling spatial segregation of nanoclusters and modulating information transduction.
Denay J.K. Richards, Brandon M. Trejo, Parijat Sil…·Danelle Devenport
This study shows melanoblasts use atypical E-cadherin attachments to migrate through epithelial layers without disrupting the barrier.
Ashley C. Humphries, Claudia Molina-Pelayo, Parijat Sil…·Marek Mlodzik
The paper shows that phosphorylation of a specific tyrosine in Vang/Vangl regulates its interaction with Pk and Dsh/Dvl, promoting the formation of the Vang/Vangl-Pk complex during PCP establishment.