Mycoplasma immunoglobulin binding protein universally binds human antibodies, thereby reducing Fab arm flexibility and displacing antigens in immune complexes
Tereza Kadavá, Awital Bar Barroeta, Carla J. C. de Haas, Suzan H. M. Rooijakkers, Juergen Strasser, Johannes Preiner, Maria Nordgren, Rolf Lood, Albert J. R. Heck
This study shows that MIB protein binds all human antibody isotypes, reduces Fab flexibility, and displaces antigens in immune complexes without affecting Fc interactions.
bioRxiv · Jun 15, 2026 · PreprintBiochemistry