Johannes Preiner

This study shows that MIB protein binds all human antibody isotypes, reduces Fab flexibility, and displaces antigens in immune complexes without affecting Fc interactions.

This paper develops a kinetic model to predict IgG oligomerization and complement binding, incorporating factors like IgG concentration, antigen density, and Fc mutants.

This study shows that IgG subclass complement activation depends on their ability to form oligomers on antigen surfaces, challenging the traditional view of C1 affinity.

This study establishes quartz crystal microbalance (QCM) as a label-free method to characterize extracellular vesicles and their surface proteins, enabling improved quality control of EV-based therapeutics.