Author
Utrecht UniversityORCID 0000-0002-2059-4526Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Max L.B. Grönloh, Lisanne de Vor, Seline A. Zwarthoff…·Suzan H. M. Rooijakkers
This study shows that complement proteins like C1q block FcγR engagement with IgG, reducing their role in neutrophil phagocytosis, while complement receptors still enhance bacterial clearance.
Tereza Kadavá, Awital Bar Barroeta, Carla J. C. de Haas…·Albert J. R. Heck
This study shows that MIB protein binds all human antibody isotypes, reduces Fab flexibility, and displaces antigens in immune complexes without affecting Fc interactions.
Marije van 't Wout, Fabian Hauser, Philippa I P Holzapfel…·Dani A. C. Heesterbeek
The paper tracks MAC pore localization on E. coli and finds that MAC deposition starts at the new bacterial pole, leading to inner membrane damage and halting division.
Nienke Oskam, Maurits A. den Boer, Marie Vestergaard Lukassen…·Albert J. R. Heck
The paper identifies CD5L as a component of circulatory IgM, showing it forms a complex with J-chain-containing pentamers and affects IgM receptor binding.