Jorge Corbacho

The paper investigates ZGA timing across 61 animal species and finds that genome size to cytoplasm volume ratio predicts ZGA onset.

The paper uses single-cell multiomics to identify key regulatory nodes and cis-regulatory elements in zebrafish eye development.

The paper generates human spinal cord organoids that mimic in vivo development and identifies cell intercalation as a key mechanism for secondary neurulation.

The paper shows that vsx gene mutation in zebrafish causes bipolar cell depletion and visual impairment but maintains neural retina specification, highlighting genetic redundancy and network robustness.

The paper introduces trap-TRAP, a method to generate zebrafish transgenic lines for tissue-specific translatome analysis using TRAP combined with enhancer trap techniques.

The paper analyzes gene network bifurcation during optic cup morphogenesis in zebrafish, identifying regulatory mechanisms and conserved TF recruitment sequences in RPE specification.