Rocío Polvillo

Optic cup folding is driven by the geometry and tension of the Retinal Pigmented Epithelium (RPE) cells

The paper investigates how Wnt/β-catenin and YAP pathways regulate RPE cell geometry and tension during optic cup folding, showing their role in mechanical properties and nuclear signaling.

Single-cell multiomics identifies key nodes and cis-regulatory elements of the networks specifying the eye domains in zebrafish

The paper uses single-cell multiomics to identify key regulatory nodes and cis-regulatory elements in zebrafish eye development.

Mutation of Vsx genes in zebrafish highlights the robustness of the retinal specification network.

The paper shows that vsx gene mutation in zebrafish causes bipolar cell depletion and visual impairment but maintains neural retina specification, highlighting genetic redundancy and network robustness.

A Yap-dependent transcriptional program directs cell migration for embryo axis assembly

This study shows that Yap proteins are essential for cell migration during embryo axis formation by regulating cytoskeletal organization and cell-ECM adhesion in medaka.

Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish

The paper analyzes gene network bifurcation during optic cup morphogenesis in zebrafish, identifying regulatory mechanisms and conserved TF recruitment sequences in RPE specification.